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Volume 36, part 4
August 2008




Contents


Biochemical Society Award Lecture
Tuberculosis: a balanced diet of lipids and carbohydrates
Veemal Bhowruth, Luke J. Alderwick, Alistair K. Brown, Apoorva Bhatt and Gurdyal S. Besra..........555–565
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Heatley Medal Lecture
What we have learned from ribosome structures
V. Ramakrishnan..........567–574
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Novartis Award Lecture
The methyl-CpG-binding protein MeCP2 and neurological disease
Adrian Bird..........575–583
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Biochemical Society Linked Focus Meetings: Gene Expression and Analysis




Biochemical Society Linked Focus Meetings: Gene Expression and Analysis

Transcription
University of Manchester, U.K., 26–28 March 2008
Edited by Stefan Roberts (Manchester, U.K.) and Robert White (Beatson Institute, Glasgow, U.K.).
Transcription factories
David R.F. Carter, Christopher Eskiw and Peter R. Cook..........585–589
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Expression of human snRNA genes from beginning to end
Sylvain Egloff, Dawn O'Reilly and Shona Murphy..........590–594
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Interaction of the TFIIB zinc ribbon with RNA polymerase II
Laura M. Elsby and Stefan G.E. Roberts..........595–598
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Chromatin switching and transcriptional regulation in disease
Lezanne Ooi and Ian C. Wood..........599–602
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Regulation of the RelA (p65) transactivation domain
John M. O'Shea and Neil D. Perkins..........603–608
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The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators
Frances V. Fuller-Pace and Simak Ali..........609–612
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Switching genes on and off in haemopoiesis
David Garrick, Marco De Gobbi, Magnus Lynch and Douglas R. Higgs..........613–618
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Selected oral communications
Structure and function of ribosomal RNA gene chromatin
Joanna L. Birch and Joost C.B.M. Zomerdijk..........619–624
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Regulation of transcription by the Epstein–Barr virus nuclear antigen EBNA 2
Richard D. Palermo, Helen M. Webb, Andrea Gunnell and Michelle J. West..........625–628
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The role of the Wilms' tumour-suppressor protein WT1 in apoptosis
Jörg Hartkamp and Stefan G.E. Roberts..........629–631
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Progesterone regulation of RUSH/SMARCA3/HLTF includes DNA looping
Beverly S. Chilton and Aveline Hewetson..........632–636
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The reversal of epigenetic silencing of the EBV genome is regulated by viral bZIP protein
Questa H. Karlsson, Celine Schelcher, Elizabeth Verrall, Carlo Petosa and Alison J. Sinclair..........637–639
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Post-Transcriptional Control
University of Manchester, U.K., 26–28 March 2008
Edited by Nicola Gray (MRC Human Genetics Unit, Edinburgh, U.K.), Simon Morley (University of Sussex, U.K.) and Graham Pavitt (Manchester, U.K.).
Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein
Kirsty Sawicka, Martin Bushell, Keith A. Spriggs and Anne E. Willis..........641–647
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Subcellular localization of mRNA and factors involved in translation initiation
Nathaniel P. Hoyle and Mark P. Ashe..........648–652
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Mechanism of ribosomal subunit joining during eukaryotic translation initiation
Michael G. Acker and Jon R. Lorsch..........653–657
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Clues to the mechanism of action of eIF2B, the guanine-nucleotide-exchange factor for translation initiation
Sarah S. Mohammad-Qureshi, Martin D. Jennings and Graham D. Pavitt..........658–664
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Sequential waves of polyadenylation and deadenylation define a translation circuit that drives meiotic progression
Eulàlia Belloc, Maria Piqué and Raúl Méndez..........665–670
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Translational control in early development: CPEB, P-bodies and germinal granules
Nancy Standart and Nicola Minshall..........671–676
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Ribosomal acrobatics in post-transcriptional control
Robert J.C. Gilbert, Ian Brierley and John E.G. McCarthy..........677–683
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RNA pseudoknots and the regulation of protein synthesis
Ian Brierley, Robert J.C. Gilbert and Simon Pennell..........684–689
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Selected oral communications
Lentiviral RNAs can use different mechanisms for translation initiation
Emiliano P. Ricci, Ricardo Soto Rifo, Cécile H. Herbreteau, Didier Decimo and Théophile Ohlmann..........690–693
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Contribution of internal initiation to translation of cellular mRNAs containing IRESs
Eugenia S. Mardanova, Ludmila A. Zamchuk and Nikolai V. Ravin..........694–697
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UPF1 P-body localization
Saverio Brogna, Preethi Ramanathan and Jikai Wen..........698–700
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Regulation of translation initiation by herpesviruses
Richard W.P. Smith, Sheila V. Graham and Nicola K. Gray..........701–707
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Post-transcriptional regulation of gene expression by alternative 5′-untranslated regions in carcinogenesis
Laura Smith..........708–711
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Dissection of a co-translational nascent chain separation event
Victoria A. Doronina, Pablo de Felipe, Cheng Wu, Pamila Sharma, Matthew S. Sachs, Martin D. Ryan and Jeremy D. Brown..........712–716
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Translational termination–re-initiation in viral systems
Michael L. Powell, T. David K. Brown and Ian Brierley..........717–722
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New Methods for the Study of Protein–Nucleic Acid Interactions
University of Manchester, U.K., 26–28 March 2008
Edited by Steve Busby (Birmingham, U.K.), W. Marshall Stark (Glasgow, U.K.) and Malcolm White (St Andrews, U.K.).
The emerging role of MS in structure elucidation of protein–nucleic acid complexes
Yuliya Gordiyenko and Carol V. Robinson..........723–731
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Single-molecule micromanipulation studies of DNA and architectural proteins
Remus Th. Dame..........732–737
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Red light, green light: probing single molecules using alternating-laser excitation
Yusdi Santoso, Ling Chin Hwang, Ludovic Le Reste and Achillefs N. Kapanidis..........738–744
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Time-resolved footprinting for the study of the structural dynamics of DNA–protein interactions
Bianca Sclavi..........745–748
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Visualizing genetic loci and molecular machines in living bacteria
Xindan Wang, Rodrigo Reyes-Lamothe and David J. Sherratt..........749–753
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Methods for studying global patterns of DNA binding by bacterial transcription factors and RNA polymerase
David C. Grainger and Stephen J.W. Busby..........754–757
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Computational approaches to study transcriptional regulation
M. Madan Babu..........758–765
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The shock of the old: hydrodynamics for the masses
David J. Scott..........766–770
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Higher-throughput approaches to crystallization and crystal structure determination
Mark J. Fogg and Anthony J. Wilkinson..........771–775
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Visualizing the organization and reorganization of transcription complexes for gene expression
Patricia C. Burrows, Sivaramesh Wigneshweraraj, Dan Bose, Nicolas Joly, Jörg Schumacher, Mathieu Rappas, Tilmann Pape, Peter G. Stockley, Xiaodong Zhang and Martin Buck..........776–779
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